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Pleural effusion is the abnormal accumulation of fluid in the chest cavity. Fluid accumulates in the pleural sac, not the lungs, so the lungs are essentially floating in a chest full of fluid. This fluid occupies space within the chest, so the lungs cannot expand as fully as they should. Treatment and prognosis vary depending on the underlying cause.
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Primary liver tumors in dogs and cats are rare. There are 4 types: hepatocellular tumors, bile duct tumors, neuroendocrine tumors, and sarcomas. These cancers can be massive, nodular, or diffuse in form. In dogs, most liver tumors are malignant, while in cats, most are benign.
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Pneumothorax is an accumulation of air outside the lungs, but inside the chest wall. The air outside the lung prevents the lungs from inflating normally, and can lead to lung collapse. There are several variations of pneumothorax.
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Tumors of the urinary tract may present anywhere from the kidneys to the tip of the urethra. Tumors of the bladder are most common in the dog whereas tumors involving the kidneys are more prevalent in cats. Unfortunately, many tumors of the urinary tract are malignant and treatment options may be limited. Surgery is possible in select cases. Medical treatment may be beneficial in cases where surgery is not possible.
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Tumors of the prostate are relatively uncommon in dogs and extremely rare in cats. Clinical signs include bloody urine, or straining to urinate or defecate. Metastasis to the pelvic bone and/or lumbar spine is likely. Diagnosis and treatment options are discussed. Prognosis is considered poor.
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Malignant lymphoma (lymphosarcoma) and leukemia are among the most common malignancies seen in ferrets. Diagnosis may be made by fine needle aspiration or biopsy. For a dedicated owner with a compliant patient, surgery and/or treatment with chemotherapy is an option. Remission of lymphoma is possible with treatment in ferrets, but recurrence is common. Ferrets also commonly develop insulin-producing tumors of the pancreas that lower the ferret’s blood sugar and cause weakness, weight loss, lethargy, seizures, coma, and death. Insulinoma commonly spreads from the pancreas to the liver, so surgical removal of pancreatic insulinoma nodules may not be curative. Affected ferrets respond well for months to years to medical therapy with glucose-promoting drugs (prednisone) and anti-insulin drugs (diazoxide). Drugs suppress effects of the tumor but do not eliminate it; and ferrets on medical treatment must have their medications increased over time as the tumor grows.
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Visceral vascular tumors are tumors which arise from blood vessels. The main tumor types are hemangiosarcomas (cancerous) and hemangiomas (benign). The clinical signs vary depending on the location of the tumor. Surgery is the recommended treatment option. Given the highly metastatic nature of hemangiosarcoma, chemotherapy is also recommended.
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Common conditions of pet ferrets include diarrhea, intestinal foreign bodies, parasites, heart disease, and various tumors. This handout outlines the causes, clinical signs, and treatment options for each of these conditions. Any variation from normal should be a cause for concern and should be immediately evaluated by your veterinarian.
