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Dogs + Medications & Supplements

  • Epineprhine is a drug used most often in emergency situations for animals (e.g., anaphylaxis, cardiopulmonary resuscitation/CPR). It may be added to local anesthesia drugs due to its ability to cause veins to constrict, thus delaying the body’s absorption of the drugs and prolonging the duration of the local anesthetic duration.

  • Insulin is injected under the skin to treat diabetes, ketoacidosis, and high potassium levels. Side effects may include low or high blood sugar levels, insulin resistance, and skin allergic reactions to the injections. Do not use in pets who are having an episode of low blood sugar and do not use pork insulins in pets with a pork allergy.

  • Insulin glargine is an injectable medication used in cats, dogs, ferrets, guinea pigs, and horses with diabetes mellitus. It is used to lower blood sugar levels and for long-term maintenance therapy of diabetes mellitus. Monitor closely for signs of low blood sugar (weakness, lack of energy, lethargy, stumbling or difficulty walking, behavior changes, muscle twitching, seizures, and/or unresponsive).

  • Lente (porcine zinc) insulin (brand names Vetsulin®, Vetpen®) is an injectable medication approved for use in cats and dogs with diabetes mellitus. It is used to lower blood sugar levels and for long-term maintenance therapy of diabetes mellitus. This medication may be used "off label" or "extra label" in ferrets. Monitor closely for signs of low blood sugar (weakness, lack of energy, lethargy, stumbling or difficulty walking, behavior changes, muscle twitching, seizures, and/or unresponsiveness).

  • NPH (Neutral Protamine Hagedron) insulin is an injectable medication used in cats, dogs, birds, ferrets, and horses with diabetes mellitus. It is used to lower blood sugar levels and for long-term maintenance therapy of diabetes mellitus. Monitor closely for signs of low blood sugar (weakness, lack of energy, lethargy, stumbling or difficulty walking, behavior changes, muscle twitching, seizures, and/or unresponsiveness).

  • Protamine zinc (PZI) insulin (brand name Prozinc®) is an injectable medication approved for use in cats and dogs with diabetes mellitus. It is used to lower blood sugar levels and for long-term maintenance therapy of diabetes mellitus. This medication may be used “off label” or “extra label” in other species. Monitor closely for signs of low blood sugar (weakness, lack of energy, lethargy, stumbling or difficulty walking, behavior changes, muscle twitching, seizures, and/or unresponsiveness).

  • Butorphanol is a partial opiate agonist/antagonist that is used as an analgesic, pre-anesthetic, antitussive, or antiemetic. The injectable form is used subcutaneously, intramuscularly, or intravenously, and the tablet is given by mouth. Side effects include sedation, ataxia, anorexia, or rarely diarrhea. Caution should be used in pets with liver or kidney disease, Addison's disease, head trauma, or other CNS dysfunction, or in geriatric or severely debilitated patients.

  • Fentanyl is an opioid medication used off-label to treat pain in cats and dogs. It is often given as an injection in hospital, but patches may be prescribed to deliver fentanyl transdermally (through the skin) for pets at home. This handout describes common side effects, risk factors, and drug interactions. If a negative reaction occurs, please call your veterinary office.

  • Hydroxyurea is given by mouth and is used off label to treat certain cancers in cats and dogs. Common side effects include bone marrow suppression, lack of appetite, vomiting, diarrhea, mouth and stomach ulcers, loss of toenails and/or hair coat. Do not use in pets that are allergic to it, or in pregnant pets unless absolutely necessary. If a negative reaction occurs, please call your veterinary office.

  • Chlorambucil is given by mouth and is used off label to treat certain types of cancer and autoimmune diseases. Common side effects include fur loss and changes in hair coat, as well as gastrointestinal upset. Do not use in pets that are allergic to it or other alkylating medications, that have bone marrow disease, have an active infection, or that are pregnant or lactating. If a negative reaction occurs, please call your veterinary office.