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Small Mammals

  • Doxycycline is an antibiotic given by mouth in the form of a tablet, capsule, or liquid, used off label to treat certain infections. Common side effects include stomach upset, sun sensitivity, and increases in liver enzymes. Serious side effects include liver failure, seizures, and trouble swallowing. Do not use in pregnant pets and use cautiously in pets with liver disease or in young pets. If a negative reaction occurs, please call your veterinary office.

  • Sulfadimethoxine is an antimicrobial given by mouth in the form of a tablet or liquid suspension, used primarily to treat coccidiosis. Its use for treating small mammals and reptiles is off label. Common side effects include vomiting, diarrhea, and decreased appetite. This medication should not be used in pets that are allergic to it, pregnant, lactating, or have severe liver or kidney dysfunction. If a negative reaction occurs, call your veterinary office.

  • Tylosin is an antibiotic given by mouth or by injection in small mammals and is used off label to treat diarrhea and inflammatory bowel disease. Common side effects include decreased appetite and diarrhea. Do not use in pets that are allergic to it. If a negative reaction occurs, call your veterinary office.

  • Enrofloxacin is an antibiotic given by mouth or in the muscle commonly used to treat bacterial infections in cats, dogs, and off label in small mammals, birds, and reptiles. Common side effects include vomiting, diarrhea, and lack of appetite. It should not be used in growing or dehydrated pets, or in cats with kidney disease. Use cautiously in pets with seizures, liver, or kidney disease. If a negative reaction occurs, please call your veterinary office.

  • Leuprolide is given by injection and is used off label in ferrets and birds to treat reproductive and adrenal problems. Give as directed. Side effects in ferrets may include pain at the injection site, breathing difficulties, and sleepiness. Do not use in pets that are allergic to it or other gonadotropin-releasing hormones, and do not use in pregnant or nursing pets. If a negative reaction occurs, please call the veterinary office.

  • Azathioprine is an immune suppressing medication given by mouth or as an injection and is mainly used off label to treat immune-mediated diseases in dogs. Common side effects include gastrointestinal upset and bone marrow suppression. This medication should not be used in pets that are allergic to azathioprine or are pregnant. It should be used with caution in pets with liver or kidney disease. If a negative reaction occurs, please call your veterinary office.

  • Atenolol is used off label and given by mouth to treat certain heart conditions in dogs, cats, and ferrets. Common side effects include tiredness and stomach upset. Contraindications include hypersensitivity to beta-blockers, heart failure, heart block, low heart rate, or certain lung disease. If a negative reaction occurs, please call your veterinary office.

  • Aluminum hydroxide is commonly used off label to treat high phosphate levels in pets with kidney disease. It is given by mouth, with meals, in the form of a liquid gel, powder, or a compounded capsule. The most common side effect is constipation, and therefore it should be used with caution in pets with a gastrointestinal obstruction or pets prone to constipation. If a negative reaction occurs, please call your veterinary office.

  • Cisapride is used off label and is given by mouth to treat gastrointestinal motility disorders in cats, dogs, and small mammals. Common side effects include vomiting, diarrhea, and abdominal discomfort. Do not use in pets that are allergic to it or in pets with conditions that would be made worse by increased intestinal movement. If a negative reaction occurs, please call your veterinary office.

  • Polysulfated glycosaminoglycan is an injectable disease-modifying osteoarthritis drug (DMOAD) used to treat non-infectious and traumatic arthritis in dogs. It is also used off-label in cats and small mammals. If administering this medication at home, follow your veterinarian’s instructions and dispose of the needle and syringe appropriately. Side effects are rare when given according to label recommendations and at prescribed intervals. Do not use this medication in pets with a known hypersensitivity to it, in pets with known or suspected bleeding disorders or immune-mediated arthritis, or in pets with severe kidney or liver disorders.