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  • Desmopressin is administered into the eye or is given as an injection and is used off label to treat diabetes insipidus and von Willebrand disease. Give as directed by your veterinarian. Side effects are uncommon but may include irritation upon application to the eye. Do not use in pets that are allergic to it or pets that are prone to blood clots, such as those with heart disease. If a negative reaction occurs, please call your veterinary office.

  • Doxepin is given by mouth and is used off label to treat psychogenic dermatoses such as excessive grooming and psychogenic alopecia. Give as directed. The most common side effect is sleepiness. Do not use in pets that are allergic to it or other tricyclic antidepressants, in pets currently using an MAOI or flea/tick collar, or in pets undergoing skin allergy testing within two weeks. If a negative reaction occurs, please call your veterinary office.

  • Bismuth compounds are given by mouth and are used on and off label to treat diarrhea and upset stomach. Give as directed by your veterinarian. The most common side effects include discolored stools and constipation. Do not use in pets that are allergic to it or other NSAIDs, or in pets that have a stomach or intestinal ulcer. If a negative reaction occurs, please call your veterinary office.

  • Diethylstilbestrol is given by mouth and is used off label to treat urinary incontinence. Give as directed by your veterinarian. Side effects are uncommon when using a low dose, but may include mild vaginal spotting. It should not be used in pets that are allergic to it, in females with estrogen-sensitive tumors, in pets with anemia or low white blood cell counts, or in food production animals. If a negative reaction occurs, please call your veterinary office.

  • Fludrocortisone acetate is given by mouth and is used off label to treat hypoadrenocorticism (Addison’s disease) and hyperkalemia. Give as directed by your veterinarian. Side effects are uncommon but may include vomiting. Do not use in pets that are allergic to it or in lactating pets without using a milk replacer. If a negative reaction occurs, please call your veterinary office.

  • Hydroxyzine is given by mouth or injection and is used off label to treat allergic or itchy conditions. Give as directed. The most common side effect is sedation. Do not use in pets that are allergic to it or cetirizine, or pets that have heart failure, urinary obstruction, or stomach obstruction. If a negative reaction occurs, please call your veterinary office.

  • Mometasone combinations are applied topically to the skin and are used on and off label to treat skin lesions. The most common side effect is inflammation at the application site. It should not be used on pets that are allergic to it, are pregnant, have tuberculosis of the skin, or in pets with a ruptured ear drum. If a negative reaction occurs, please call your veterinary office.

  • Phenoxybenzamine is given by mouth and is used off label to treat urination difficulty related to sphincter tone, high blood pressure related to pheochromocytoma, and laminitis in horses. Phenoxybenzamine should be given as directed by your veterinarian. Common side effects include nausea, vomiting, diarrhea, small pupils, increased heart rate, and nasal congestion/stuffy nose. Do not use in pets that are allergic to it, in pets that cannot handle low blood pressure, or in horses with colic. If a negative reaction occurs, please call your veterinary office.

  • Pyridostigmine bromide is given by mouth or injection and is used off label to treat symptoms related to myasthenia gravis. Give as directed. Dose-related side effects include drooling, diarrhea, increased urination, abdominal pain, muscle cramps, and increased tear production. Do not use in pets that are allergic to it or other bromides, or in pets that have urinary or gastrointestinal tract obstructions or blockages. If a negative reaction occurs, please call your veterinary office.

  • Triamcinolone acetonide is given by mouth or injection and is used on and off label to treat Addison’s disease, inflammatory conditions, and immune-mediated diseases. Give as directed. Common side effects include increased drinking, increased urination, and increased appetite. Do not use in pets that are allergic to it, or pets with systemic fungal infections, viral infections, ulcers, tuberculosis, or Cushing’s disease. If a negative reaction occurs, please call your veterinary office.