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  • Telmisartan is an angiotensin receptor blocker (ARB) used to treat high blood pressure in cats and off-label to treat kidney disease in both cats and dogs. This medication is given by mouth in the form of a liquid or tablet. It may be given with or without food but is better absorbed if given on an empty stomach. Side effects may include vomiting, diarrhea, lack of appetite, low blood pressure, and decreased energy. There are several drugs that can contribute to adverse effects when given with telmisartan. Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

  • Pentosan polysulfate sodium is an injectable disease-modifying osteoarthritis drug (DMOAD) used to treat non-infectious and traumatic arthritis in dogs. It is also used off-label in cats. Follow your veterinarian’s instructions on how to administer the injection and dispose of the needle and syringe appropriately. Side effects are rare when given according to label recommendations and at prescribed intervals. Do not use in pets with a known hypersensitivity to it, in pets with known or suspected bleeding disorders or immune-mediated arthritis, or in pets with severe kidney or liver disorders.

  • Clonidine is a medication that is used to treat behavioral disorders in dogs, particularly anxiety or phobia-related. Give as directed. Side effects are generally mild if present and include sedation, lethargy, agitation/excitation, aggression, and constipation. Monitoring blood pressure as well as heart rate and rhythm is recommended with chronic use. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

  • Sarolaner is given by mouth and is used to treat flea and tick infestations and has also been used off-label to treat certain types of mange and mites. Give as directed. Side effects are uncommon but may include stomach upset or neurologic symptoms. Do not use in pets with a history of seizures. If a negative reaction occurs, please call the veterinary office.

  • Prazosin is given by mouth and is used to reduce urinary sphincter tone to relax the bladder and allow easier urination in dogs and cats. It may also be used as a treatment for congestive heart failure, systemic hypertension, or pulmonary hypertension in dogs. Give as directed. Common side effects include lethargy, vomiting, diarrhea, nausea, and constipation. This medication should be used with caution in pets with kidney disease or other conditions that cause low blood pressure, as well as in MDR1-positive dogs. If a negative reaction occurs, contact your veterinarian.

  • Moxidectin is an avermectin antiparasitic that is used to prevent heartworms and treat intestinal parasites. Imidacloprid treats and prevents fleas. These two drugs are combined in one topical product for use in cats, dogs, and ferrets. Use as directed. Side effects are uncommon and usually short-lived, however, if you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

  • Minocycline is given by mouth and is used off-label to treat certain bacterial infections and as a part of the heartworm treatment protocol. Give as directed. Common side effects include stomach upset, such as vomiting, decreased appetite, and diarrhea. Do not use in pets that are allergic to it or that are pregnant, nursing, or are very young. If a negative reaction occurs, call your veterinarian.

  • Sucralfate is given by mouth and is used off-label to treat ulcers and erosions in the mouth, esophagus, stomach, and upper small intestine. Give as directed. Side effects are uncommon but may include constipation. Do not use in pets that are allergic to this medication. If a negative reaction occurs, please call your veterinarian.

  • Omeprazole is given by mouth and is used off-label to treat ulcers and erosions in the stomach and upper small intestine. Give as directed. Side effects are uncommon but may include stomach upset, such as vomiting, diarrhea, or gas. Do not use in pets with a history of allergies to this class of drugs. If a negative reaction occurs, call your veterinarian.

  • Silymarin is an over-the-counter nutritional supplement that is used off-label and is given by mouth to treat liver and cancer conditions. Give as directed. Side effects are uncommon but may include vomiting or diarrhea. Do not use it in pets that are allergic to it. If a negative reaction occurs, please call the veterinary office.