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  • Silymarin is an over-the-counter nutritional supplement that is used off-label and is given by mouth to treat liver and cancer conditions. Give as directed. Side effects are uncommon but may include vomiting or diarrhea. Do not use it in pets that are allergic to it. If a negative reaction occurs, please call the veterinary office.

  • Metoclopramide is given by mouth or injection and is used off-label to treat gastrointestinal motility disorders, nausea, and vomiting in dogs, cats, and other animals. Give as directed. Side effects are uncommon but may include restlessness, hyperactivity, muscle twitches, drowsiness, and increased urination. Do not use in pets with intestinal blockage or bleeding, pseudopregnancy, pheochromocytoma, or a history of seizures or head trauma. If a negative reaction occurs, contact your veterinarian.

  • Metronidazole is given by mouth or injection and is used off-label to treat certain anaerobic bacterial and protozoal infections and gastrointestinal conditions in dogs, cats, and other animals. Give as directed. Side effects may include nausea, vomiting, diarrhea, regurgitation, decreased appetite, tiredness, and drooling. Do not use in pets that are allergic to it, are debilitated, or are pregnant or nursing. If a negative reaction occurs, contact your veterinarian.

  • Pyrantel pamoate is given by mouth and is used on and off label to treat intestinal parasites in many species. Give as directed. Side effects are uncommon but may include stomach upset, such as vomiting or diarrhea. Do not use in pets that are allergic to it. If a negative reaction occurs, call your veterinarian.

  • Ranitidine is given by mouth or injection and is used off-label to treat ulcers and erosions in the stomach and upper small intestine, reflux, or gastrointestinal motility issues. Give as directed. Side effects are uncommon but may include stomach upset. Do not use in pets with a history of allergies to this class of drugs. If a negative reaction occurs, call your veterinarian.

  • Trifluridine is an antiviral topical medication used to treat viral infections of the eye, such as herpesvirus-1 in cats. Give as directed. Side effects include eye irritation. Do not use in pets with an allergy to this medication. If a negative reaction occurs, please call the veterinary office.

  • Mirtazapine is given by mouth or is applied to the skin and is used to treat weight loss in cats and is used off-label to treat inappetence, nausea, and vomiting in cats and dogs. Give as directed. The most common side effects include vocalization, restlessness, vomiting, incoordination, or trembling. Do not use it in pets that are allergic to it or that have recently used an MAOI. If a negative reaction occurs, call your veterinarian.

  • Your veterinarian may prescribe rectal medication if your pet is unable to swallow oral medications or if a specific required medication cannot be effectively absorbed with oral delivery. The rectal tissues contain large numbers of blood vessels very close to their surface, which means that medications delivered to this area are rapidly absorbed into the bloodstream. Rectal medication is most commonly used to treat seizures.

  • Enzymes are given by mouth and are used over the counter or as a prescription to treat digestion problems, pain, or inflammation. Give as directed by your veterinarian. Side effects may include vomiting, diarrhea, and allergic reactions. Do not use in pets that are allergic to the enzyme or the source of the enzyme. Use cautiously in pets with liver or kidney disease, or in pets that are pregnant or nursing. If a negative reaction occurs, please call your veterinary office.

  • Flower essences are an over the counter supplement given by mouth or applied topically to treat stress or anxiety. Give as directed by your veterinarian. There are no known side effects. Do not use in pets that are allergic to it or that are pregnant or nursing. Flower essences should be used cautiously in debilitated pets or pets in organ failure. If a negative reaction occurs, please call your veterinary office.