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Your veterinarian may prescribe rectal medication if your pet is unable to swallow oral medications or if a specific required medication cannot be effectively absorbed with oral delivery. The rectal tissues contain large numbers of blood vessels very close to their surface, which means that medications delivered to this area are rapidly absorbed into the bloodstream. Rectal medication is most commonly used to treat seizures.
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Imatinib is given by mouth and is used off label to treat certain types of cancers in dogs and cats. Give as directed. Side effects may include nausea, vomiting, muscle pain, diarrhea, skin rash, or lack of energy. Do not use in pets that are pregnant or nursing. If a negative reaction occurs, call the veterinary office.
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Warfarin is given by mouth and is used off label to treat abnormal clotting in dogs and occasionally horses. Give as directed. The most common side effect is abnormal bleeding, and this should be reported to your veterinarian. Do not use in pets that are allergic to it, pets with bleeding diseases, active bleeding, aneurysm, acute kidney disease, brain bleeds, blood cell diseases, uncontrolled high blood pressure, liver disease, certain types of carcinoma, pets about to undergo certain surgical procedures, or pets that are pregnant. If a negative reaction occurs, please call the veterinary office.
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Sildenafil is given by mouth or injection and is used off label to treat high blood pressure in the lungs or to treat megaesophagus. Give as directed. Side effects are uncommon but may include vomiting, diarrhea, decreased appetite, or skin redness in the groin area. Do not use in pets that are allergic to it or pets that take nitrate medications. If a negative reaction occurs, please call your veterinarian.
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Lokivetmab is given by injection and is used on and off label to treat itchiness in dogs. Give as directed. Side effects are uncommon but may include vomiting, diarrhea, sleepiness, lack of appetite, or pain at the injection site. Do not use in pets that are allergic to it. If a negative reaction occurs, please call the veterinary office.
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Deslorelin is injected under the skin or into the muscle and is used on and off-label in horses, ferrets, and dogs to treat reproductive and adrenal conditions (off-label use in the U.S. is prohibited). Give as directed. Common side effects include swelling, sensitivity, redness, and warmth at the injection site. Do not use in pets that are allergic to it. If a negative reaction occurs, please call the veterinary office.
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Low molecular weight heparin is given by injection under the skin and is used off label to treat abnormal blood clots. Give as directed. Side effects may include pain at the injection site. Do not use in pets that are allergic to any type of heparin or pork products. If a negative reaction occurs, call the veterinary office.
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Tadalafil is given by mouth or injection and is used off label to treat high blood pressure in the lungs. Give as directed. Side effects may include vomiting, diarrhea, decreased appetite, or skin redness in the groin area. Do not use in pets that are allergic to it or pets that take nitrate medications. If a negative reaction occurs, please call the veterinary office.
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An increase in your pet’s breathing rate while resting quietly or sleeping is an early clinical sign that your pet may be developing heart failure and needs to see your veterinarian. In general, all normal dogs and cats have a breathing rate of between 15-30 breaths per minute when they are resting. Resting breathing rates that are consistently greater than 30 breaths per minute are increased and considered abnormal. One breath is counted when the chest has moved in and out once. Typically, your veterinarian will have you count the breathing rate once per day for a week while you are learning and then will set up a schedule depending on your pet’s heart health status.
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Clopidogrel is given by mouth in the form of a tablet or compounded liquid and is used off label to prevent abnormal blood clots in dogs, cats, and horses. Give as directed by your veterinarian. Common side effects include vomiting, diarrhea, or lack of appetite. Do not use in pets that are allergic to it or that have bleeding problems. If a negative reaction or bleeding occurs, please call your veterinary office.
