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  • Silymarin is an over-the-counter nutritional supplement that is used off-label and is given by mouth to treat liver and cancer conditions. Give as directed. Side effects are uncommon but may include vomiting or diarrhea. Do not use it in pets that are allergic to it. If a negative reaction occurs, please call the veterinary office.

  • Metoclopramide is given by mouth or injection and is used off-label to treat gastrointestinal motility disorders, nausea, and vomiting in dogs, cats, and other animals. Give as directed. Side effects are uncommon but may include restlessness, hyperactivity, muscle twitches, drowsiness, and increased urination. Do not use in pets with intestinal blockage or bleeding, pseudopregnancy, pheochromocytoma, or a history of seizures or head trauma. If a negative reaction occurs, contact your veterinarian.

  • Metronidazole is given by mouth or injection and is used off-label to treat certain anaerobic bacterial and protozoal infections and gastrointestinal conditions in dogs, cats, and other animals. Give as directed. Side effects may include nausea, vomiting, diarrhea, regurgitation, decreased appetite, tiredness, and drooling. Do not use in pets that are allergic to it, are debilitated, or are pregnant or nursing. If a negative reaction occurs, contact your veterinarian.

  • Pyrantel pamoate is given by mouth and is used on and off label to treat intestinal parasites in many species. Give as directed. Side effects are uncommon but may include stomach upset, such as vomiting or diarrhea. Do not use in pets that are allergic to it. If a negative reaction occurs, call your veterinarian.

  • Ranitidine is given by mouth or injection and is used off-label to treat ulcers and erosions in the stomach and upper small intestine, reflux, or gastrointestinal motility issues. Give as directed. Side effects are uncommon but may include stomach upset. Do not use in pets with a history of allergies to this class of drugs. If a negative reaction occurs, call your veterinarian.

  • Finasteride is given by mouth and is used off-label to treat benign prostatic hypertrophy (enlarged prostate) in intact male dogs, and may also be used for adrenal problems in ferrets. Give as directed. Side effects are uncommon. Do not use it in sexually developing animals or in females, including pregnant or nursing females. If a negative reaction occurs, please call your veterinarian.

  • Trifluridine is an antiviral topical medication used to treat viral infections of the eye, such as herpesvirus-1 in cats. Give as directed. Side effects include eye irritation. Do not use in pets with an allergy to this medication. If a negative reaction occurs, please call the veterinary office.

  • Idoxuridine is an antiviral topical medication used to treat viral infections of the eye, such as feline herpesvirus-1 in cats. Idoxuridine comes as eye drops or can be compounded by your veterinarian into an eye ointment. Give as directed. Side effects of idoxuridine include eye irritation. Pregnant women should NOT handle this medication.

  • Mirtazapine is given by mouth or is applied to the skin and is used to treat weight loss in cats and is used off-label to treat inappetence, nausea, and vomiting in cats and dogs. Give as directed. The most common side effects include vocalization, restlessness, vomiting, incoordination, or trembling. Do not use it in pets that are allergic to it or that have recently used an MAOI. If a negative reaction occurs, call your veterinarian.

  • Famciclovir is given by mouth and is used off-label to control feline herpesvirus. Give as directed. Side effects may include vomiting, diarrhea, decreased appetite, and increased drinking and urination. Do not use it in pets that are allergic to it or penciclovir. If a negative reaction occurs, call your veterinary office.