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  • Bromides are given by mouth and are used off label to treat seizures in dogs. Common side effects include sleepiness, mild vomiting, restlessness, increased or decreased appetite, constipation, increased thirst, and increased urination. Do not use bromides in cats or in pets that are allergic to it. If a negative reaction occurs, please call your veterinary office.

  • Buprenorphine is used on and off label and is given by mouth into the cheek or by injection to treat pain or as a preanesthetic. The most common side effect is sleepiness. Do not use in pets that are allergic to it or other opioids, or in pets being treated with amitraz. If a negative reaction occurs, please call your veterinary office.

  • Esafoxolaner + eprinomectin + praziquantel is given topically on the skin to treat and protect against various internal and external parasites and prevent heartworm in cats. Side effects are rare but may include hair loss at the application site, gastrointestinal upset, skin reactions, or neurologic signs. Use caution in sick or underweight cats. If a negative reaction occurs, please call your veterinary office.

  • Benazepril is given by mouth and is used on and off label to treat heart failure, high blood pressure, chronic kidney disease, protein-losing glomerulonephropathies, and idiopathic kidney bleeding. Side effects may include vomiting, diarrhea, and lack of appetite. Do not use in pets that are allergic to it or other ACE inhibitors. If a negative reaction occurs, call your veterinary office.

  • Terbinafine oral tablets or granules are commonly used off label to treat skin or systemic fungal infections in dogs and cats. Common side effects are primarily gastrointestinal, such as vomiting, inappetence, and diarrhea, and should be used with caution in patients with liver or kidney disease. If treating with this medication long-term, your veterinarian will perform periodic blood tests to check liver function and monitor for any changes or elevations.

  • Terbinafine cream or spray is occasionally used off label to treat skin fungal infections in dogs, or in a veterinary combination product to treat ear infections. It is ineffective for treating fungal skin infections in cats. When given as directed, side effects are rarely noted, but could include skin irritation.

  • Ketoconazole otic is an antifungal used in the treatment of external ear infections (otitis externa) caused by yeast in cats, dogs, and other animals. Ketoconazole otic comes in ointment or liquid drop suspension forms that may be specially compounded and/or combined into a formulation with other medications.

  • Ketoconazole topical is an antifungal used in the treatment of skin infections caused by fungal organisms in cats, dogs, and other animals. It comes in a variety of forms that may be specially compounded and/or be combined with other medications.

  • Imidacloprid and pyriproxyfen (brand names Advantage®II, Advantage Plus®, Provecta®II) is a topical (spot-on) antiparasitic drug used to repel and kill fleas and lice in dogs and puppies that are at least 7 weeks of age and weigh at least 1.36 kg (3 lb). This medication is labeled for treatment of flea infestations in cats and kittens that are at least 7-8 weeks of age and weigh at least 0.9 kg (2 lb) or 2.3kg (5 lb), depending on the product. Imidacloprid and pyriproxyfen comes in topical solution form that is applied directly to the skin. Do not confuse this medication with K9 Advantix®II, Provecta® Advanced, or Activate®II, similar products labeled for use in dogs only, as those medications contain permethrin, which is toxic to cats.

  • Imidacloprid with flumethrin (brand name Seresto® collar) is a topical antiparasitic drug contained in a collar used for control of fleas, ticks, and chewing lice on dogs and puppies at least 7 weeks of age. This medication is labeled for control of fleas and ticks in cats and kittens that are at least 10 weeks of age. Imidacloprid with flumethrin comes in a collar impregnated with the medication that, if used properly, is effective for 8 months.