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  • Carprofen is a nonsteroidal anti-inflammatory drug (NSAID) used on and off label. It is given by mouth in the form of a tablet to treat pain and inflammation. The most common side effects include vomiting, diarrhea, and decreased appetite. Do not use this medication in pets with bleeding disorders, in pets that are allergic to it or other NSAIDs in the same class, or in pets concurrently using corticosteroids or other NSAIDs. If a negative reaction occurs, call your veterinary office.

  • Clonazepam is given by mouth and is used off label to treat seizures and certain behavioral disorders. Common side effects include sleepiness, incoordination, drooling, excitement, or increased appetite. Do not use in pets that are allergic to it or other benzodiazepines or in pets with significant liver disease. If a negative reaction occurs, please call your veterinary office.

  • Codeine is given by mouth or injection and is used off label to treat mild to moderate pain, cough, and occasionally diarrhea. Give as directed by your veterinarian. Common side effects include sleepiness and constipation. Do not use in pets that are allergic to it or other opioids, in pets with inflammatory bowel disease, or in pets that have ingested a toxic substance. If a negative reaction occurs, please call your veterinary office.

  • Diazepam is given by mouth, injection, or into the rectum and is used off label to treat anxiety, seizures, tense muscles, or decreased appetite. Give as directed by your veterinarian. Side effects include sleepiness, increased appetite, incoordination, weakness, agitation, drooling, and aggression. Do not give to cats by mouth, and do not use in pets that are allergic to it or other benzodiazepines, or in pets with severe liver disease. If a negative reaction occurs, please call your veterinary office.

  • Phenobarbital is given by mouth or as an injection to treat seizures or to sedate your pet. Common side effects include sleepiness, increased thirst, urination, and/or appetite. Do not use this medication in pets with liver, lung, or kidney disease or those that are allergic to barbiturates. If a negative reaction occurs, call your veterinary office.

  • Tramadol is a synthetic opioid given by mouth in the form of a tablet, capsule, or compounded liquid, and is used off label to treat pain. Common side effects include sedation, gastrointestinal upset, or agitation. It should not be used in pets that are hypersensitive to opioids, and should be used cautiously in geriatric, sick, or pets with seizures. If a negative reaction occurs, call your veterinary office.

  • Doxycycline is an antibiotic given by mouth in the form of a tablet, capsule, or liquid, used off label to treat certain infections. Common side effects include stomach upset, sun sensitivity, and increases in liver enzymes. Serious side effects include liver failure, seizures, and trouble swallowing. Do not use in pregnant pets and use cautiously in pets with liver disease or in young pets. If a negative reaction occurs, please call your veterinary office.

  • Rifampin is commonly used off label to treat infections in horses, and occasionally in dogs and cats. It is usually given by mouth in the form of a capsule or compounded liquid. The most common side effects are vomiting, diarrhea, or reduced appetite. Liver dysfunction is possible. A change in the color of urine, tears, and saliva to a red/orange color is expected but may stain fabrics. Use with caution in pets that have pre-existing liver disease, are pregnant, are elderly, or are lactating. If a negative reaction occurs, call your veterinary office.

  • Sulfadimethoxine is an antimicrobial given by mouth in the form of a tablet or liquid suspension, used primarily to treat coccidiosis. Its use for treating small mammals and reptiles is off label. Common side effects include vomiting, diarrhea, and decreased appetite. This medication should not be used in pets that are allergic to it, pregnant, lactating, or have severe liver or kidney dysfunction. If a negative reaction occurs, call your veterinary office.

  • Tylosin is an antibiotic given by mouth or by injection in small mammals and is used off label to treat diarrhea and inflammatory bowel disease. Common side effects include decreased appetite and diarrhea. Do not use in pets that are allergic to it. If a negative reaction occurs, call your veterinary office.