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  • Allopurinol is an oral medication typically used to prevent uric acid and calcium oxalate stones in dogs. It is also used off-label to treat leishmaniasis and gout in dogs and other species. Side effects are uncommon but may involve stomach upset. Caution must be taken when allopurinol is used in conjunction with certain other medications. It should not be used in pets with liver or kidney dysfunction or in red-tailed hawks.

  • Cephalexin (brand names Rilexine®, Keflex®, Vetolexin®) is an oral antibiotic used to treat pyoderma and other bacterial skin infections in dogs and is used off-label in cats to treat pyoderma and other types of skin infections. It is sometimes used off-label to treat urinary tract infections in cats and dogs. Side effects of cephalexin are rare and usually mild.

  • Your veterinarian may prescribe rectal medication if your pet is unable to swallow oral medications or if a specific required medication cannot be effectively absorbed with oral delivery. The rectal tissues contain large numbers of blood vessels very close to their surface, which means that medications delivered to this area are rapidly absorbed into the bloodstream. Rectal medication is most commonly used to treat seizures.

  • Imatinib is given by mouth and is used off label to treat certain types of cancers in dogs and cats. Give as directed. Side effects may include nausea, vomiting, muscle pain, diarrhea, skin rash, or lack of energy. Do not use in pets that are pregnant or nursing. If a negative reaction occurs, call the veterinary office.

  • Low molecular weight heparin is given by injection under the skin and is used off label to treat abnormal blood clots. Give as directed. Side effects may include pain at the injection site. Do not use in pets that are allergic to any type of heparin or pork products. If a negative reaction occurs, call the veterinary office.

  • An increase in your pet’s breathing rate while resting quietly or sleeping is an early clinical sign that your pet may be developing heart failure and needs to see your veterinarian. In general, all normal dogs and cats have a breathing rate of between 15-30 breaths per minute when they are resting. Resting breathing rates that are consistently greater than 30 breaths per minute are increased and considered abnormal. One breath is counted when the chest has moved in and out once. Typically, your veterinarian will have you count the breathing rate once per day for a week while you are learning and then will set up a schedule depending on your pet’s heart health status.

  • Clopidogrel is given by mouth in the form of a tablet or compounded liquid and is used off label to prevent abnormal blood clots in dogs, cats, and horses. Give as directed by your veterinarian. Common side effects include vomiting, diarrhea, or lack of appetite. Do not use in pets that are allergic to it or that have bleeding problems. If a negative reaction or bleeding occurs, please call your veterinary office.

  • Enzymes are given by mouth and are used over the counter or as a prescription to treat digestion problems, pain, or inflammation. Give as directed by your veterinarian. Side effects may include vomiting, diarrhea, and allergic reactions. Do not use in pets that are allergic to the enzyme or the source of the enzyme. Use cautiously in pets with liver or kidney disease, or in pets that are pregnant or nursing. If a negative reaction occurs, please call your veterinary office.

  • Flower essences are an over the counter supplement given by mouth or applied topically to treat stress or anxiety. Give as directed by your veterinarian. There are no known side effects. Do not use in pets that are allergic to it or that are pregnant or nursing. Flower essences should be used cautiously in debilitated pets or pets in organ failure. If a negative reaction occurs, please call your veterinary office.

  • Medicinal mushrooms are given by mouth and are used over the counter (and under veterinary supervision) to supplement the treatment of cancer and other conditions. Give as directed by your veterinarian. Side effects may include stomach upset, diarrhea, dizziness, and skin rash. Do not use in pets that are allergic to mushrooms, and use cautiously in pets that are pregnant, nursing, or have diabetes, clotting disorders, low blood pressure, immune-mediated disorders, liver problems, or kidney disease. If a negative reaction occurs, please call your veterinary office.