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  • Dextromethorphan is given by mouth and is used off label to treat compulsive behaviors and occasionally used to treat cough. Side effects are uncommon but may include vomiting, diarrhea, decreased appetite, sleepiness, drooling or anxiousness. Do not use in pets that are allergic to it.

  • Dexamethasone is given on and off label, by mouth or injection, to treat various inflammatory, autoimmune, and adrenal gland conditions. It can also be used off label as a diagnostic test. Common side effects include increased drinking, urination and/or appetite, dull/dry haircoat, weight gain, pot-bellied appearance, muscle weakness, panting, vomiting, or diarrhea.

  • Clarithromycin is given by mouth and used off label to treat certain bacterial infections in several animal species. Do not use in pets that are allergic to it or other macrolide antibiotics, in rabbits, gerbils, guinea pigs, hamsters, or horses greater than four months old.

  • Clarithromycin is given by mouth and used off label to treat certain bacterial infections in several animal species. Do not use in pets that are allergic to it or other macrolide antibiotics, in rabbits, gerbils, guinea pigs, hamsters, or horses more than four months old.

  • Calcitriol is used off label and is given by mouth or injection to treat low blood calcium levels associated with low parathyroid hormone, as well as chronic kidney disease, certain cancers, and certain skin diseases. Side effects are uncommon if the dose is appropriate.

  • Buprenorphine is used on and off label and is given by mouth into the cheek or by injection to treat pain or as a preanesthetic. The most common side effect is sleepiness. Do not use in pets that are allergic to it or other opioids, or in pets being treated with amitraz. If a negative reaction occurs, please call your veterinary office.

  • Esafoxolaner + eprinomectin + praziquantel is given topically on the skin to treat and protect against various internal and external parasites and prevent heartworm in cats. Side effects are rare but may include hair loss at the application site, gastrointestinal upset, skin reactions, or neurologic signs. Use caution in sick or underweight cats. If a negative reaction occurs, please call your veterinary office.

  • Benazepril is given by mouth and is used on and off label to treat heart failure, high blood pressure, chronic kidney disease, protein-losing glomerulonephropathies, and idiopathic kidney bleeding. Side effects may include vomiting, diarrhea, and lack of appetite. Do not use in pets that are allergic to it or other ACE inhibitors. If a negative reaction occurs, call your veterinary office.

  • Terbinafine oral tablets or granules are commonly used off label to treat skin or systemic fungal infections in dogs and cats. Common side effects are primarily gastrointestinal, such as vomiting, inappetence, and diarrhea, and should be used with caution in patients with liver or kidney disease. If treating with this medication long-term, your veterinarian will perform periodic blood tests to check liver function and monitor for any changes or elevations.

  • Terbinafine cream or spray is occasionally used off label to treat skin fungal infections in dogs, or in a veterinary combination product to treat ear infections. It is ineffective for treating fungal skin infections in cats. When given as directed, side effects are rarely noted, but could include skin irritation.