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  • Famotidine is an antacid given by mouth or into the vein and is commonly used off label to treat gastrointestinal ulcers and acid reflux. Side effects are uncommon but may include a slow heart rate, stomach upset, or dry mouth and skin. Use cautiously in pets that are geriatric or have liver, kidney, or heart disease.

  • Fluoxetine is given by mouth and is used on and off label to treat various behavioral conditions. Common side effects include sleepiness and decreased appetite. If a negative reaction occurs, call your veterinary office.

  • Dextromethorphan is given by mouth and is used off label to treat compulsive behaviors and occasionally used to treat cough. Side effects are uncommon but may include vomiting, diarrhea, decreased appetite, sleepiness, drooling or anxiousness. Do not use in pets that are allergic to it.

  • Dexamethasone is given on and off label, by mouth or injection, to treat various inflammatory, autoimmune, and adrenal gland conditions. It can also be used off label as a diagnostic test. Common side effects include increased drinking, urination and/or appetite, dull/dry haircoat, weight gain, pot-bellied appearance, muscle weakness, panting, vomiting, or diarrhea.

  • Clarithromycin is given by mouth and used off label to treat certain bacterial infections in several animal species. Do not use in pets that are allergic to it or other macrolide antibiotics, in rabbits, gerbils, guinea pigs, hamsters, or horses greater than four months old.

  • Decoquinate is given by mouth and is used off label in dogs to prevent coccidia infections. Side effects are uncommon. Do not use in animals that are allergic to it or to treat coccidia infections (only use as a preventive).

  • Clarithromycin is given by mouth and used off label to treat certain bacterial infections in several animal species. Do not use in pets that are allergic to it or other macrolide antibiotics, in rabbits, gerbils, guinea pigs, hamsters, or horses more than four months old.

  • Buprenorphine is used on and off label and is given by mouth into the cheek or by injection to treat pain or as a preanesthetic. The most common side effect is sleepiness. Do not use in pets that are allergic to it or other opioids, or in pets being treated with amitraz. If a negative reaction occurs, please call your veterinary office.

  • Calcitriol is used off label and is given by mouth or injection to treat low blood calcium levels associated with low parathyroid hormone, as well as chronic kidney disease, certain cancers, and certain skin diseases. Side effects are uncommon if the dose is appropriate.

  • Bromides are given by mouth and are used off label to treat seizures in dogs. Common side effects include sleepiness, mild vomiting, restlessness, increased or decreased appetite, constipation, increased thirst, and increased urination. Do not use bromides in cats or in pets that are allergic to it. If a negative reaction occurs, please call your veterinary office.