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Small Mammals

  • Sulfasalazine is given by mouth and is used off label to treat inflammatory large bowel disease and vasculitis. Give as directed by your veterinarian. Side effects include dry eye, decreased appetite, vomiting, yellowing of the skin, eyes, or body fluids. Do not use in pets that are allergic to it or other sulfonamides or salicylates, or in Doberman Pinschers, Miniature Schnauzers, or Samoyeds, or in pets with dry eye/KCS, intestinal or urinary blockages, or severe dehydration. If a negative reaction occurs, please call your veterinary office.

  • Loperamide is given by mouth and is used off label to treat signs of diarrhea. Give as directed by your veterinarian. Common side effects include constipation, bloat, and sleepiness. Do not use in pets that are allergic to it, that have diarrhea due to an infection or a toxin, or that are positive for the MDR1 gene. If a negative reaction occurs, please call your veterinary office.

  • Diazoxide is given by mouth and is used off label to treat low blood sugar associated with insulin-producing tumors of the pancreas. Give as directed by your veterinarian. Common side effects include drooling, lack of appetite, vomiting, and diarrhea. Do not use in pets that are allergic to it or thiazide diuretics, or in pets with low blood sugar due to anything other than a tumor. If a negative reaction occurs, please call your veterinary office.

  • Bismuth compounds are given by mouth and are used on and off label to treat diarrhea and upset stomach. Give as directed by your veterinarian. The most common side effects include discolored stools and constipation. Do not use in pets that are allergic to it or other NSAIDs, or in pets that have a stomach or intestinal ulcer. If a negative reaction occurs, please call your veterinary office.

  • Fludrocortisone acetate is given by mouth and is used off label to treat hypoadrenocorticism (Addison’s disease) and hyperkalemia. Give as directed by your veterinarian. Side effects are uncommon but may include vomiting. Do not use in pets that are allergic to it or in lactating pets without using a milk replacer. If a negative reaction occurs, please call your veterinary office.

  • Hydroxyzine is given by mouth or injection and is used off label to treat allergic or itchy conditions. Give as directed. The most common side effect is sedation. Do not use in pets that are allergic to it or cetirizine, or pets that have heart failure, urinary obstruction, or stomach obstruction. If a negative reaction occurs, please call your veterinary office.

  • Prednisone/prednisolone is given by mouth or injection and is used on and off label to treat Addison’s disease, inflammatory conditions, neoplasia (cancer), and immune-mediated diseases. Give this medication as directed by your veterinarian. Common side effects include increased drinking, increased urination, and increased appetite. Do not use in pets that are allergic to it, or pets with systemic fungal infections, viral infections, ulcers, tuberculosis, or Cushing’s disease. If a negative reaction occurs, please call your veterinary office.

  • Tetracycline is given by mouth and is used off label to treat bacterial infections and inflammatory skin conditions in many animal species. The most common side effects include nausea, vomiting, diarrhea, and lack of appetite. Do not use in pets that are allergic to it or other tetracycline antibiotics, or in pregnant animals, especially in the first half of pregnancy. If a negative reaction occurs, please call your veterinary office.

  • Chlorpheniramine maleate is given by mouth and is used off label to treat allergic conditions or as a mild sedative. Common side effects include sleepiness, although other side effects are possible. Do not use in pets that are allergic to it or other similar antihistamines, or pets that are undergoing allergy testing within 2 weeks. If a negative reaction occurs, please call your veterinary office.

  • Selemectin is used topically on the skin to treat various parasites, both on and off label. Side effects are rare but may include hair loss at application site, gastrointestinal upset, skin reactions, or neurologic signs. Use with caution in sick or underweight pets, or dogs with the MDR1 mutation. If a negative reaction occurs, please call your veterinary office.